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A Fruit Fly Embryo Montage

These brilliant photos, taken by the lab of Dr. Stephen W. Paddock from the University of Wisconsin, are various stages of embryonic development in Drosophila (fruit flies).  Fruit flies are extremely useful (and popular) model organisms for studying developmental biology, basic biological processes, population genetics and other basic genetic processes (like mutation and disease).

Captions From the Stephen Paddock Digital Image Gallery

1 and 2- Triple-labeled Drosophila embryo at the cellular blastoderm stage. The specimen was immunofluorescently tagged with antibodies to the hairy protein in red, Kruppel repressor in green and the giant protein in blue. 

3- The central nervous system of a Drosophila (fruit fly) embryo captured in a serial optical section by confocal laser scanning microscopy. This double-labeled fluorescent specimen reveals peripheral neurons in green and glial cells in red.

4- Presented below is a color mapped image of a Drosophila embryo, featuring stripes of the engrailed gene, which circle the embryo. The engrailed gene helps to direct fruit fly wing development, and mutations in this gene can affect how the wings appear in adult flies.

5- A tripled labeled fruit fly imaginal disc (developmental tissues from which many adult structures, such as eyes, wings, and halteres, are formed)

6- Triple-labeled Drosophila eye imaginal disc recovered from the third instar larval developmental stage.

These images are some of my favorites.  Visit the gallery to see more amazing microscopy from this lab!

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via Oh Yeah, Developmental Biology!
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